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Analysis of drug resistance in HIV protease

Abstract Background Drug resistance in HIV is the major problem limiting effective antiviral therapy. Computational techniques for predicting drug resistance profiles from genomic data can accelerate the appropriate choice of therapy. These techniques can also be used to select protease mutants for...

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Autori principali: Shrikant D. Pawar, Christopher Freas, Irene T. Weber, Robert W. Harrison
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2018-10-01
Serie:BMC Bioinformatics
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RBM
Accesso online:http://link.springer.com/article/10.1186/s12859-018-2331-y
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