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Evolution of Conformational Disorder & Diversity of the P53 Interactome
The tumour suppressor p53 is now known to be an ancient transcription factor that had already evolved interaction sites with its partner protein MDM2 at the dawn of multi-cellular eukaryotic animal life. The billion-year life history of the p53-MDM2 axis has permitted significant time for the protei...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Pensoft Publishers
2013-08-01
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Colecção: | BioDiscovery |
Acesso em linha: | https://biodiscovery.pensoft.net/article/8952/download/pdf/ |
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