HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice

Inflammatory bowel disease (IBD) is a chronic inflammatory disease, in which the intestinal epithelium loses its barrier function. Given the existence of the oxygen gradient in the intestinal epithelium and that inflammation further contributes to the tissue hypoxia, we investigated the role of hypo...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Young-Eun Kim, Minji Lee, Hyejung Gu, Jeongwoo Kim, Seongju Jeong, Sujin Yeo, You Jeong Lee, Sin-Hyeog Im, Young-Chul Sung, Hak Jae Kim, Irving L. Weissman, G-One Ahn
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Company of Biologists 2018-07-01
Sarja:Disease Models & Mechanisms
Aiheet:
Hypoxia-inducible factor
Myeloid cells
Dextran sodium sulfate
Colitis
Linkit:http://dmm.biologists.org/content/11/7/dmm033241
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