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HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice
Inflammatory bowel disease (IBD) is a chronic inflammatory disease, in which the intestinal epithelium loses its barrier function. Given the existence of the oxygen gradient in the intestinal epithelium and that inflammation further contributes to the tissue hypoxia, we investigated the role of hypo...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2018-07-01
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| Colecção: | Disease Models & Mechanisms |
| Assuntos: | |
| Acesso em linha: | http://dmm.biologists.org/content/11/7/dmm033241 |
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