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Parameters Affecting Image-guided, Hydrodynamic Gene Delivery to Swine Liver
Development of a safe and effective method for gene delivery to hepatocytes is a critical step toward gene therapy for liver diseases. Here, we assessed the parameters for gene delivery to the livers of large animals (pigs, 40–65 kg) using an image-guided hydrodynamics-based procedure that involves...
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Autores principales: | , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
Elsevier
2013-01-01
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Colección: | Molecular Therapy: Nucleic Acids |
Materias: | |
Acceso en línea: | http://www.sciencedirect.com/science/article/pii/S2162253116301846 |
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