Parameters Affecting Image-guided, Hydrodynamic Gene Delivery to Swine Liver

Development of a safe and effective method for gene delivery to hepatocytes is a critical step toward gene therapy for liver diseases. Here, we assessed the parameters for gene delivery to the livers of large animals (pigs, 40–65 kg) using an image-guided hydrodynamics-based procedure that involves...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Kenya Kamimura, Takeshi Suda, Guisheng Zhang, Yutaka Aoyagi, Dexi Liu
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2013-01-01
Colección:Molecular Therapy: Nucleic Acids
Materias:
gene therapy
human α-1 antitrypsin
hydrodynamic gene delivery
image-guided gene delivery
non-viral vector
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2162253116301846
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares