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Machine learning modeling of family wide enzyme-substrate specificity screens.

Biocatalysis is a promising approach to sustainably synthesize pharmaceuticals, complex natural products, and commodity chemicals at scale. However, the adoption of biocatalysis is limited by our ability to select enzymes that will catalyze their natural chemical transformation on non-natural substr...

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Detalhes bibliográficos
Main Authors: Samuel Goldman, Ria Das, Kevin K Yang, Connor W Coley
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2022-02-01
Colecção:PLoS Computational Biology
Acesso em linha:https://doi.org/10.1371/journal.pcbi.1009853
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