CASCADE: high-throughput characterization of regulatory complex binding altered by non-coding variants

Summary: Non-coding DNA variants (NCVs) impact gene expression by altering binding sites for regulatory complexes. New high-throughput methods are needed to characterize the impact of NCVs on regulatory complexes. We developed CASCADE (Customizable Approach to Survey Complex Assembly at DNA Elements...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Principais autores: David Bray, Heather Hook, Rose Zhao, Jessica L. Keenan, Ashley Penvose, Yemi Osayame, Nima Mohaghegh, Xiaoting Chen, Sreeja Parameswaran, Leah C. Kottyan, Matthew T. Weirauch, Trevor Siggers
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-02-01
coleção:Cell Genomics
Assuntos:
cofactor
transcription factor
recruitment
single-nucleotide polymorphism
screen
logo
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2666979X22000155
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados