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Dietary Choline Alleviates High-Fat Diet-Induced Hepatic Lipid Dysregulation via UPRmt Modulated by SIRT3-Mediated mtHSP70 Deacetylation

The mitochondrial unfolded protein response (UPRmt) is known as a conservative mechanism in response to mitochondrial dysfunction. Thus, based on UPRmt, this study was conducted to determine the mechanism of a high-fat diet (HFD) inducing mitochondrial dysfunction and its role in stimulating hepatic...

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Main Authors: Yu-Feng Song, Hua Zheng, Zhi Luo, Christer Hogstrand, Zhen-Yu Bai, Xiao-Lei Wei
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
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Acceso en liña:https://www.mdpi.com/1422-0067/23/8/4204
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