EpiMethEx: a tool for large-scale integrated analysis in methylation hotspots linked to genetic regulation

Abstract Background DNA methylation is an epigenetic mechanism of genomic regulation involved in the maintenance of homeostatic balance. Dysregulation of DNA methylation status is one of the driver alterations occurring in neoplastic transformation and cancer progression. The identification of methy...

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Detalhes bibliográficos
Main Authors: Saverio Candido, Giuseppe Alessandro Parasiliti Palumbo, Marzio Pennisi, Giulia Russo, Giuseppe Sgroi, Valentina Di Salvatore, Massimo Libra, Francesco Pappalardo
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-02-01
Colecção:BMC Bioinformatics
Assuntos:
DNA methylation
Gene expression
R package
Acesso em linha:http://link.springer.com/article/10.1186/s12859-018-2397-6
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