Disordered–Ordered Protein Binary Classification by Circular Dichroism Spectroscopy

Intrinsically disordered proteins lack a stable tertiary structure and form dynamic conformational ensembles due to their characteristic physicochemical properties and amino acid composition. They are abundant in nature and responsible for a large variety of cellular functions. While numerous bioinf...

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Hauptverfasser: András Micsonai, Éva Moussong, Nikoletta Murvai, Ágnes Tantos, Orsolya Tőke, Matthieu Réfrégiers, Frank Wien, József Kardos
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2022-05-01
Schriftenreihe:Frontiers in Molecular Biosciences
Schlagworte:
intrinsically disordered proteins
CD spectroscopy
protein secondary structure
disorder identifier
disorder–order classification
machine learning
Online Zugang:https://www.frontiersin.org/articles/10.3389/fmolb.2022.863141/full
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