Long non-coding RNA LINC00520 promotes the proliferation and metastasis of malignant melanoma by inducing the miR-125b-5p/EIF5A2 axis

Abstract Background Long intergenic non-protein coding RNA 520 (LINC00520), a novel identified lncRNA, has been shown to modulate the malignant phenotype of tumor cells in some malignant tumors. However, the exact role and molecular mechanism of LINC00520 in malignant melanoma has not been studied....

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Autori principali: Wenkang Luan, Yuting Ding, Haitao Yuan, Shaojun Ma, Hongru Ruan, Jinlong Wang, Feng Lu, Xuefeng Bu
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2020-05-01
Serie:Journal of Experimental & Clinical Cancer Research
Soggetti:
Melanoma
Growth and metastasis
LICN00520
miR-125b-5p
EIF5A2
Accesso online:http://link.springer.com/article/10.1186/s13046-020-01599-7
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