Exosomal miR-106b-5p derived from melanoma cell promotes primary melanocytes epithelial-mesenchymal transition through targeting EphA4

BACKGROUND: Cancer-secreted exosomal miRNAs regulates the biological processes of many tumours. The serum level of exosomal miR-106b-5p is significantly increased in melanoma patients. However, the role and molecular mechanisms of exosomal miR-106b-5p in melanoma remains unclear. METHODS: Quantitati...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Exp Clin Cancer Res
Auteurs principaux: Luan, Wenkang, Ding, Yuting, Xi, Haolan, Ruan, Hongru, Lu, Feng, Ma, Shaojun, Wang, Jinlong
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980627/
https://ncbi.nlm.nih.gov/pubmed/33741023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01906-w
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