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Proteomic Identification of LASP-1 Down-regulation After RNAi Urokinase Silencing in Human Hepatocellular Carcinoma Cells

In human hepatocellular carcinoma (HCC), the high expression of urokinase-type plasminogen activator (uPA) is an unfavorable prognostic factor and a therapeutic target. To identify the downstream effects of uPA silencing by RNA interference, we studied proteome modifications of uPA-inhibited SKHep1C...

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Detalhes bibliográficos
Main Authors: Alessandro Salvi, Italia Bongarzone, Francesca Miccichè, Bruna Arici, Sergio Barlati, Giuseppina De Petro
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2009-02-01
Colecção:Neoplasia: An International Journal for Oncology Research
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S147655860980033X
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