Overexpression of Mineralocorticoid Receptors in the Mouse Forebrain Partly Alleviates the Effects of Chronic Early Life Stress on Spatial Memory, Neurogenesis and Synaptic Function in the Dentate Gyrus

Evidence from human studies suggests that high expression of brain mineralocorticoid receptors (MR) may promote resilience against negative consequences of stress exposure, including childhood trauma. We examined, in mice, whether brain MR overexpression can alleviate the effects of chronic early li...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sofia Kanatsou, Henk Karst, Despoina Kortesidou, Rachelle A. van den Akker, Jan den Blaauwen, Anjanette P. Harris, Jonathan R. Seckl, Harm J. Krugers, Marian Joels
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017-05-01
Colecção:Frontiers in Cellular Neuroscience
Assuntos:
mineralocorticoid receptor
early life stress
mouse
hippocampus
spatial memory
synaptic transmission
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fncel.2017.00132/full
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados