Overexpression of Mineralocorticoid Receptors Partially Prevents Chronic Stress-Induced Reductions in Hippocampal Memory and Structural Plasticity.

Exposure to chronic stress is a risk factor for cognitive decline and psychopathology in genetically predisposed individuals. Preliminary evidence in humans suggests that mineralocorticoid receptors (MRs) may confer resilience to these stress-related changes. We specifically tested this idea using a...

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Autores principales: Sofia Kanatsou, Brenna C Fearey, Laura E Kuil, Paul J Lucassen, Anjanette P Harris, Jonathan R Seckl, Harm Krugers, Marian Joels
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2015-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC4658081?pdf=render
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