Methylglyoxal Acts as a Tumor-Promoting Factor in Anaplastic Thyroid Cancer

Methylglyoxal (MG) is a potent inducer of advanced glycation end products (AGEs). MG, long considered a highly cytotoxic molecule with potential anticancer value, is now being re-evaluated to a protumorigenic agent in some malignancies. Anaplastic thyroid cancer (ATC) is an extremely aggressive and...

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Main Authors: Cinzia Antognelli, Sonia Moretti, Roberta Frosini, Efisio Puxeddu, Angelo Sidoni, Vincenzo N. Talesa
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2019-06-01
Series:Cells
Assuntos:
methylglyoxal
anaplastic thyroid cancer
glyoxalase 1
EMT
AGEs
resveratrol
aminoguanidine
Acceso en liña:https://www.mdpi.com/2073-4409/8/6/547
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