Oleuropein-Induced Apoptosis Is Mediated by Mitochondrial Glyoxalase 2 in NSCLC A549 Cells: A Mechanistic Inside and a Possible Novel Nonenzymatic Role for an Ancient Enzyme

Oleuropein (OP) is a bioactive compound derived from plants of the genus Oleaceae exhibiting antitumor properties in several human cancers, including non-small-cell lung cancer (NSCLC). Recent evidence suggests that OP has proapoptotic effects on NSCLC cells via the mitochondrial apoptotic pathway....

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Antognelli, Cinzia, Frosini, Roberta, Santolla, Maria F., Peirce, Matthew J., Talesa, Vincenzo N.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679873/
https://ncbi.nlm.nih.gov/pubmed/31428230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8576961
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