Differential Expression of Acid – Sensing Ion Channels in Mouse Primary Afferents in Naïve and Injured Conditions

Injury and inflammation cause tissue acidosis, which is a common feature of various painful conditions. Acid-Sensing Ion channels (ASICs) are amongst the main excitatory channels activated by extracellular protons and expressed in the nervous system. Six transcripts of ASIC subunits including ASIC1a...

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Main Authors: Melina Papalampropoulou-Tsiridou, Simon Labrecque, Antoine G. Godin, Yves De Koninck, Feng Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-05-01
Colecção:Frontiers in Cellular Neuroscience
Assuntos:
dorsal root ganglia
peripheral nerve injury
in situ hybridization
neuropathic pain
peptidergic afferents
Acesso em linha:https://www.frontiersin.org/article/10.3389/fncel.2020.00103/full
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