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Genetic risk for Alzheimer’s disease is concentrated in specific macrophage and microglial transcriptional networks
Abstract Background Genome-wide association studies of Alzheimer’s disease (AD) have identified a number of significant risk loci, the majority of which lie in non-coding regions of the genome. The lack of causal alleles and considerable polygenicity remains a significant barrier to translation into...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2018-02-01
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| Colecção: | Genome Medicine |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s13073-018-0523-8 |
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