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Development and Biochemical Characterization of Self-Immolative Linker Containing GnRH-III-Drug Conjugates

The human gonadotropin releasing hormone (GnRH-I) and its sea lamprey analogue GnRH-III specifically bind to GnRH receptors on cancer cells and can be used as targeting moieties for targeted tumor therapy. Considering that the selective release of drugs in cancer cells is of high relevance, we were...

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Main Authors: Sabine Schuster, Éva Juhász, Gábor Halmos, Ines Neundorf, Cesare Gennari, Gábor Mező
格式: Artigo
語言:Inglês
出版: MDPI AG 2022-05-01
叢編:International Journal of Molecular Sciences
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在線閱讀:https://www.mdpi.com/1422-0067/23/9/5071
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