Pseudomonas aeruginosa Polynucleotide Phosphorylase Contributes to Ciprofloxacin Resistance by Regulating PrtR

Pseudomonas aeruginosa is an opportunistic bacterial pathogen that causes various acute and chronic infections. It is intrinsically resistant to a variety of antibiotics. However, production of pyocins during SOS response sensitizes P. aeruginosa to quinolone antibiotics by inducing cell lysis. The...

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Main Authors: Zheng Fan, Hao Chen, Mei Li, Xiaolei Pan, Weixin Fu, Huan Ren, Ronghao Chen, Fang Bai, Yongxin Jin, Zhihui Cheng, Shouguang Jin, Weihui Wu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-07-01
Colecção:Frontiers in Microbiology
Assuntos:
Pseudomonas aeruginosa
polynucleotide phosphorylase
ciprofloxacin resistance
PrtR
pyocins
Acesso em linha:https://www.frontiersin.org/article/10.3389/fmicb.2019.01762/full
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