Endothelial Cdc42 deficiency impairs endothelial regeneration and vascular repair after inflammatory vascular injury

Abstract Background Endothelial cell (EC) regeneration is essential for inflammation resolution and vascular integrity recovery after inflammatory vascular injury. Cdc42 is a central regulator of cell survival and vessel formation in EC development. However, it is unknown that whether Cdc42 could be...

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Autores principales: Jiawen Lv, Junchao Zeng, Fukun Guo, Yiran Li, Mengying Xu, Yuanxiong Cheng, Lin Zhang, Shaoxi Cai, Yinghua Chen, Yi Zheng, Guodong Hu
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2018-02-01
Colección:Respiratory Research
Materias:
ALI/ARDS
Pulmonary microvascular injury and repair
Cre/Loxp technique
Cdc42
PAK1/AKT pathway
Acceso en línea:http://link.springer.com/article/10.1186/s12931-018-0729-8
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