Endothelial Cdc42 deficiency impairs endothelial regeneration and vascular repair after inflammatory vascular injury

Abstract Background Endothelial cell (EC) regeneration is essential for inflammation resolution and vascular integrity recovery after inflammatory vascular injury. Cdc42 is a central regulator of cell survival and vessel formation in EC development. However, it is unknown that whether Cdc42 could be...

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Detalhes bibliográficos
Main Authors: Jiawen Lv, Junchao Zeng, Fukun Guo, Yiran Li, Mengying Xu, Yuanxiong Cheng, Lin Zhang, Shaoxi Cai, Yinghua Chen, Yi Zheng, Guodong Hu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-02-01
Colecção:Respiratory Research
Assuntos:
ALI/ARDS
Pulmonary microvascular injury and repair
Cre/Loxp technique
Cdc42
PAK1/AKT pathway
Acesso em linha:http://link.springer.com/article/10.1186/s12931-018-0729-8
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