IgE re-programs alternatively-activated human macrophages towards pro-inflammatory anti-tumoural statesResearch in context

Background: Antibody Fc-driven engagement of macrophages is critical for evoking cellular activation and effector functions and influencing tumour-associated macrophage (TAM) recruitment. We previously reported that IgE class antibodies promote restriction of cancer growth in rodent models associate...

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Main Authors: Giulia Pellizzari, Coran Hoskin, Silvia Crescioli, Silvia Mele, Jelena Gotovina, Giulia Chiaruttini, Rodolfo Bianchini, Kristina Ilieva, Heather J. Bax, Sophie Papa, Katie E. Lacy, Erika Jensen-Jarolim, Sophia Tsoka, Debra H. Josephs, James F. Spicer, Sophia N. Karagiannis
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019-05-01
Serija:EBioMedicine
Online dostop:http://www.sciencedirect.com/science/article/pii/S2352396419302257
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