Elevated Markers of Death Receptor-Activated Apoptosis are Associated with Increased Risk for Development of Diabetes and Cardiovascular Disease

Background: An increased rate of cell death by apoptosis has been implicated in both diabetes and atherosclerosis. Apoptosis can be induced through activation of the death receptors TNF receptor 1 (TNFR-1), TRAIL receptor 2 (TRAILR-2) and Fas. Soluble forms of these receptors are found in plasma. Th...

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Main Authors: Ingrid Yao Mattisson, Harry Björkbacka, Maria Wigren, Andreas Edsfeldt, Olle Melander, Gunilla Nordin Fredrikson, Eva Bengtsson, Isabel Gonçalves, Marju Orho-Melander, Gunnar Engström, Peter Almgren, Jan Nilsson
Format: Artigo
Language:Inglês
Published: Elsevier 2017-12-01
Series:EBioMedicine
Subjects:
Apoptosis
Diabetes mellitus
Myocardial infarction
Ischemic stroke
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417304668
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