Elevated Markers of Death Receptor-Activated Apoptosis are Associated with Increased Risk for Development of Diabetes and Cardiovascular Disease

BACKGROUND: An increased rate of cell death by apoptosis has been implicated in both diabetes and atherosclerosis. Apoptosis can be induced through activation of the death receptors TNF receptor 1 (TNFR-1), TRAIL receptor 2 (TRAILR-2) and Fas. Soluble forms of these receptors are found in plasma. Th...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Mattisson, Ingrid Yao, Björkbacka, Harry, Wigren, Maria, Edsfeldt, Andreas, Melander, Olle, Fredrikson, Gunilla Nordin, Bengtsson, Eva, Gonçalves, Isabel, Orho-Melander, Marju, Engström, Gunnar, Almgren, Peter, Nilsson, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836474/
https://ncbi.nlm.nih.gov/pubmed/29208468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.11.023
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