Molecular Discrimination of Sheep Bovine Spongiform Encephalopathy from Scrapie

Sheep CH1641-like transmissible spongiform encephalopathy isolates have shown molecular similarities to bovine spongiform encephalopathy (BSE) isolates. We report that the prion protein PrPSc from sheep BSE is extremely resistant to denaturation. This feature, combined with the N-terminal PrPSc clea...

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Main Authors: Laura Pirisinu, Sergio Migliore, Michele Angelo Di Bari, Elena Esposito, Thierry Baron, Claudia D’Agostino, Luigi De Grossi, Gabriele Vaccari, Umberto Agrimi, Romolo Nonno
Formato: Artigo
Idioma:Inglês
Publicado: Centers for Disease Control and Prevention 2011-04-01
Series:Emerging Infectious Diseases
Assuntos:
Prions
transmissible spongiform encephalopathy
scrapie
bovine spongiform encephalopathy
BSE
CH1641
Acceso en liña:https://wwwnc.cdc.gov/eid/article/17/4/10-1215_article
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