Proteins Involved in Synaptic Plasticity Are Downregulated in the Cerebrospinal Fluid of Infants With Clinical Sepsis Complicated by Neuroinflammation

Newborn infants are prone to sepsis and related inflammation of different organs. Neuroinflammation has been associated with long-term adverse neuronal (neuropsychiatric/neurodegenerative) outcomes, including attention deficit hyperactivity disorder (ADHD) or even Alzheimer's disease. Despite a...

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Autori principali: Ping-Ping Jiang, Shan-Shan Peng, Stanislava Pankratova, Ping Luo, Ping Zhou, You Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2022-05-01
Serie:Frontiers in Cellular Neuroscience
Soggetti:
neonatal sepsis
neuroinflammation
CSF
proteomics
amyloid-β precursor protein (APP)
Accesso online:https://www.frontiersin.org/articles/10.3389/fncel.2022.887212/full
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