Proteins Involved in Synaptic Plasticity Are Downregulated in the Cerebrospinal Fluid of Infants With Clinical Sepsis Complicated by Neuroinflammation

Newborn infants are prone to sepsis and related inflammation of different organs. Neuroinflammation has been associated with long-term adverse neuronal (neuropsychiatric/neurodegenerative) outcomes, including attention deficit hyperactivity disorder (ADHD) or even Alzheimer's disease. Despite a...

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Bibliographic Details
Main Authors: Ping-Ping Jiang, Shan-Shan Peng, Stanislava Pankratova, Ping Luo, Ping Zhou, You Chen
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neonatal sepsis
neuroinflammation
CSF
proteomics
amyloid-β precursor protein (APP)
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2022.887212/full
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