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Simultaneous Quantification of Protein Binding Kinetics in Whole Cells with Surface Plasmon Resonance Imaging and Edge Deformation Tracking

Most drugs work by binding to receptors on the cell surface. Quantification of binding kinetics between drug and membrane protein is an essential step in drug discovery. Current methods for measuring binding kinetics involve extracting the membrane protein and labeling, and both have issues. Surface...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wenwen Jing, Ashley Hunt, Nongjian Tao, Fenni Zhang, Shaopeng Wang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2020-09-01
Cyfres:Membranes
Pynciau:
Mynediad Ar-lein:https://www.mdpi.com/2077-0375/10/9/247
Tagiau: Ychwanegu Tag
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