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Down-regulation of the interferon signaling pathway in T lymphocytes from patients with metastatic melanoma.

Dysfunction of the immune system has been documented in many types of cancers. The precise nature and molecular basis of immune dysfunction in the cancer state are not well defined.To gain insights into the molecular mechanisms of immune dysfunction in cancer, gene expression profiles of pure sorted...

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Detalhes bibliográficos
Main Authors: Rebecca J Critchley-Thorne, Ning Yan, Serban Nacu, Jeffrey Weber, Susan P Holmes, Peter P Lee
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2007-05-01
Colecção:PLoS Medicine
Acesso em linha:http://europepmc.org/articles/PMC1865558?pdf=render
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