Development of a novel multi-functional integrated bioconjugate effectively targeting K-Ras mutant pancreatic cancer

Folate receptor (FR) overexpression occurs in a variety of cancers, including pancreatic cancer. In addition, enhanced macropinocytosis exists in K-Ras mutant pancreatic cancer. Furthermore, the occurrence of intensive desmoplasia causes a hypoxic microenvironment in pancreatic cancer. In this study...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Yang-Yang Wang, Liang Li, Xiu-Jun Liu, Qing-Fang Miao, Yi Li, Meng-Ran Zhang, Yong-Su Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-04-01
Colecção:Journal of Pharmaceutical Analysis
Assuntos:
Pancreatic cancer
Folate receptor
Multi-functional
Macropinocytosis-enhanced
Bioconjugate
K-Ras
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2095177921000708
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados