Cigarette Smoke Disturbs the Survival of CD8+ Tc/Tregs Partially through Muscarinic Receptors-Dependent Mechanisms in Chronic Obstructive Pulmonary Disease.

CD8+ T cells (Cytotoxic T cells, Tc) are known to play a critical role in the pathogenesis of smoking related airway inflammation including chronic obstructive pulmonary disease (COPD). However, how cigarette smoke directly impacts systematic CD8+ T cell and regulatory T cell (Treg) subsets, especia...

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Main Authors: Gang Chen, Mei Zhou, Long Chen, Zhao-Ji Meng, Xian-Zhi Xiong, Hong-Ju Liu, Jian-Bao Xin, Jian-Chu Zhang
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2016-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC4726532?pdf=render
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