Cigarette Smoking Promotes Inflammation in Patients with COPD by Affecting the Polarization and Survival of Th/Tregs through Up-Regulation of Muscarinic Receptor 3 and 5 Expression

BACKGROUND: CD4(+) T cells in the lung are involved in the pathogenesis of chronic obstructive pulmonary disease (COPD), although CD4(+) T cell subsets and the direct effect of smoking on these cells, especially the expression of MRs, have not been comprehensively examined. METHODS: First, circulati...

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Vydáno v:PLoS One
Hlavní autoři: Zhang, Ming-Qiang, Wan, Yong, Jin, Yang, Xin, Jian-Bao, Zhang, Jian-Chu, Xiong, Xian-Zhi, Chen, Long, Chen, Gang
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223024/
https://ncbi.nlm.nih.gov/pubmed/25375131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112350
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