Novel somatic single nucleotide variants within the RNA binding protein hnRNP A1 in multiple sclerosis patients [v1; ref status: indexed, http://f1000r.es/3nv]

Some somatic single nucleotide variants (SNVs) are thought to be pathogenic, leading to neurological disease. We hypothesized that heterogeneous nuclear ribonuclear protein A1 (hnRNP A1), an autoantigen associated with multiple sclerosis (MS) would contain SNVs. MS patients develop antibodies to hnR...

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Главные авторы: Sangmin Lee, Michael Levin
Формат: Artigo
Язык:Inglês
Опубликовано: F1000 Research Ltd 2014-06-01
Серии:F1000Research
Предметы:
Medical Genetics
Multiple Sclerosis & Related Disorders
Neurogenetics
Online-ссылка:http://f1000research.com/articles/3-132/v1
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