Novel somatic single nucleotide variants within the RNA binding protein hnRNP A1 in multiple sclerosis patients [v1; ref status: indexed, http://f1000r.es/3nv]

Some somatic single nucleotide variants (SNVs) are thought to be pathogenic, leading to neurological disease. We hypothesized that heterogeneous nuclear ribonuclear protein A1 (hnRNP A1), an autoantigen associated with multiple sclerosis (MS) would contain SNVs. MS patients develop antibodies to hnR...

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Detalhes bibliográficos
Main Authors: Sangmin Lee, Michael Levin
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Ltd 2014-06-01
Colecção:F1000Research
Assuntos:
Medical Genetics
Multiple Sclerosis & Related Disorders
Neurogenetics
Acesso em linha:http://f1000research.com/articles/3-132/v1
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