Discovery of Kynurenines Containing Oligopeptides as Potent Opioid Receptor Agonists

Kynurenine (kyn) and kynurenic acid (kyna) are well-defined metabolites of tryptophan catabolism collectively known as “kynurenines”, which exert regulatory functions in host-microbiome signaling, immune cell response, and neuronal excitability. Kynurenine containing peptides end...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Edina Szűcs, Azzurra Stefanucci, Marilisa Pia Dimmito, Ferenc Zádor, Stefano Pieretti, Gokhan Zengin, László Vécsei, Sándor Benyhe, Marianna Nalli, Adriano Mollica
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI AG 2020-02-01
श्रृंखला:Biomolecules
विषय:
peptides
kynurenines
binding affinity
μ-opioid receptor
pharmacophore
g-protein activation
ऑनलाइन पहुंच:https://www.mdpi.com/2218-273X/10/2/284
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