Insulin-like growth factor role in determining the anti-cancer effect of metformin: RCT in prostate cancer patients

Objective: Androgen deprivation therapy (ADT), a principal therapy in patients with prostate cancer, is associated with the development of obesity, insulin resistance, and hyperinsulinemia. Recent evidence indicates that metformin may slow cancer progression and improves survival in prostate cancer...

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Bibliografski detalji
Glavni autori: Vita Birzniece, Mark McLean, Navneeta Reddy, Haleh Shahidipour, Amy Hayden, Howard Gurney, Glenn Stone, Rikke Hjortebjerg, Jan Frystyk
Format: Artigo
Jezik:Inglês
Izdano: Bioscientifica 2022-05-01
Serija:Endocrine Connections
Teme:
igfbp-3
bioactive igf-1
pregnancy-associated plasma protein-a
stanniocalcin 2
insulin resistance
Online pristup:https://ec.bioscientifica.com/view/journals/ec/11/4/EC-21-0375.xml
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