Heterologous Production of a Novel Cyclic Peptide Compound, KK-1, in Aspergillus oryzae

A novel cyclic peptide compound, KK-1, was originally isolated from the plant-pathogenic fungus Curvularia clavata. It consists of 10 amino acid residues, including five N-methylated amino acid residues, and has potent antifungal activity. Recently, the genome-sequencing analysis of C. clavata was c...

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Detalhes bibliográficos
Main Authors: Akira Yoshimi, Sigenari Yamaguchi, Tomonori Fujioka, Kiyoshi Kawai, Katsuya Gomi, Masayuki Machida, Keietsu Abe
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-04-01
Colecção:Frontiers in Microbiology
Assuntos:
antifungal activity
Aspergillus oryzae
gene cluster
heterologous production
non-ribosomal peptide
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00690/full
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