Loss of XBP1 accelerates age-related decline in retinal function and neurodegeneration

Abstract Background Aging is the strongest risk factor for neurodegenerative diseases and extended age results in neuronal degeneration and functional decline in the visual system. Among many contributing factors to age-related deterioration of neurons is an insufficient activation of the Unfolded P...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Todd McLaughlin, Marek Falkowski, Jae Whan Park, Stephen Keegan, Michael Elliott, Joshua J. Wang, Sarah X. Zhang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2018-04-01
Serier:Molecular Neurodegeneration
Fag:
X-box binding protein 1
Aging
Retina
Neurodegeneration
Unfolded protein response
Online adgang:http://link.springer.com/article/10.1186/s13024-018-0250-z
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker