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Loss of XBP1 accelerates age-related decline in retinal function and neurodegeneration
Abstract Background Aging is the strongest risk factor for neurodegenerative diseases and extended age results in neuronal degeneration and functional decline in the visual system. Among many contributing factors to age-related deterioration of neurons is an insufficient activation of the Unfolded P...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2018-04-01
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| Colecção: | Molecular Neurodegeneration |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s13024-018-0250-z |
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