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Seneca Valley Virus 2C and 3Cpro Induce Apoptosis via Mitochondrion-Mediated Intrinsic Pathway

Seneca Valley virus (SVV) is the only member of the genus Senecavirus of the Picornaviridae family. SVV can selectively infect and lyse tumor cells with neuroendocrine features and is used as an oncolytic virus for treating small-cell lung cancers. However, the detailed mechanism underlying SVV-medi...

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Main Authors: Tingting Liu, Xiangmin Li, Mengge Wu, Liuxing Qin, Huanchun Chen, Ping Qian
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2019-05-01
叢編:Frontiers in Microbiology
主題:
2C
在線閱讀:https://www.frontiersin.org/article/10.3389/fmicb.2019.01202/full
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