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Method Validation for Analysis of Simvastatin in Human Plasma Using Liquid Chromatography Tandem Mass Spectrometry (LC-MS-MS)

Introduction: The Liquid Chromatography Tandem Mass Spectrometry (LC-MS-MS) for determination simvastatin in human plasma has been developed after extraction by by ethyl acetate and hexane (90/10%, v/v) using lovastatin as internal standard. Material and Methods: The mobile phase consisting of...

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Autor principal: Khaled M.Alakhali
Formato: Artigo
Idioma:Inglês
Publicado em: JCDR Research and Publications Private Limited 2013-12-01
Colecção:Journal of Clinical and Diagnostic Research
Assuntos:
Acesso em linha:https://jcdr.net/articles/PDF/3748/25-%206261_F(P)_PF1(Bo_PP)_PFA(P)_FA(T)_PF1(PUH)_PF1(SH)_PF3(PR).pdf
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