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PODOCYTE-SPECIFIC OVEREXPRESSION OF SIRT-1 INCREASES NEPHRIN IN OBESE MICE FED A HIGH-FAT DIET

Obesity can lead to inflammation, hyperlipidemia, diabetes, hypertension, and renal dysfunction, and is also associated with proteinuria. Histopathological changes in the glomeruli in obesity were characterized by glomerulomegaly and focal segmental glomerulosclerosis. This study was designed to inv...

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Detalhes bibliográficos
Main Authors: Han Byoung-Geun, Cui Jun, Yang Jae-Won, Choi Seung-Ok
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Nephrology 2012-06-01
Colecção:Kidney Research and Clinical Practice
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211913212004275
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