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In vivo RNAi screen reveals neddylation genes as novel regulators of Hedgehog signaling.
Hedgehog (Hh) signaling is highly conserved in all metazoan animals and plays critical roles in many developmental processes. Dysregulation of the Hh signaling cascade has been implicated in many diseases, including cancer. Although key components of the Hh pathway have been identified, significant...
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Main Authors: | , , , , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Public Library of Science (PLoS)
2011-01-01
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Sraith: | PLoS ONE |
Rochtain Ar Líne: | http://europepmc.org/articles/PMC3169580?pdf=render |
Clibeanna: |
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