Urine Assay to Measure Tenofovir Concentrations in Patients Taking Tenofovir Alafenamide

Background: HIV pre-exposure prophylaxis (PrEP) with tenofovir/emtricitabine is effective when taken daily. Previously, we developed a urine assay capable of detecting the prodrug tenofovir (TFV) in patients taking tenofovir disoproxil fumarate (TDF)-based PrEP. However, tenofovir alafenamide (TAF)...

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Main Authors: Linden Lalley-Chareczko, Emily Hiserodt, Ganesh Moorthy, Athena Zuppa, Karam Mounzer, Helen Koenig
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-03-01
Serier:Frontiers in Pharmacology
Fag:
PrEP
HIV - human immunodeficiency virus
tenofovir alafenamide (TAF)
tenofovir
therapaeutic drug monitoring
Online adgang:https://www.frontiersin.org/article/10.3389/fphar.2020.00286/full
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