Urine Assay to Measure Tenofovir Concentrations in Patients Taking Tenofovir Alafenamide

Background: HIV pre-exposure prophylaxis (PrEP) with tenofovir/emtricitabine is effective when taken daily. Previously, we developed a urine assay capable of detecting the prodrug tenofovir (TFV) in patients taking tenofovir disoproxil fumarate (TDF)-based PrEP. However, tenofovir alafenamide (TAF)...

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Autori principali: Linden Lalley-Chareczko, Emily Hiserodt, Ganesh Moorthy, Athena Zuppa, Karam Mounzer, Helen Koenig
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020-03-01
Serie:Frontiers in Pharmacology
Soggetti:
PrEP
HIV - human immunodeficiency virus
tenofovir alafenamide (TAF)
tenofovir
therapaeutic drug monitoring
Accesso online:https://www.frontiersin.org/article/10.3389/fphar.2020.00286/full
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