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Comparing internal and external validation in the discovery of qualitative treatment-subgroup effects using two small clinical trials

In a two-arm randomized trial where both arms receive active treatment (i.e., treatments A and B), often the primary goal is to determine which of the treatments, on average, is more effective. A supplementary objective is to understand possible heterogeneity in the treatment effect by identifying m...

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Autores principales: Maren K. Olsen, Karen M. Stechuchak, Karen E. Steinhauser
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2019-09-01
Colección:Contemporary Clinical Trials Communications
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2451865418301959
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