Meckel’s Cartilage in Mandibular Development and Dysmorphogenesis

The Fgfr2cC342Y/+ Crouzon syndrome mouse model carries a cysteine to tyrosine substitution at amino acid position 342 (Cys342Tyr; C342Y) in the fibroblast growth factor receptor 2 (Fgfr2) gene equivalent to a FGFR2 mutation commonly associated with Crouzon and Pfeiffer syndromes in humans. The Fgfr2...

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Hlavní autoři: M. Kathleen Pitirri, Emily L. Durham, Natalie A. Romano, Jacob I. Santos, Abigail P. Coupe, Hao Zheng, Danny Z. Chen, Kazuhiko Kawasaki, Ethylin Wang Jabs, Joan T. Richtsmeier, Meng Wu, Susan M. Motch Perrine
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-05-01
Edice:Frontiers in Genetics
Témata:
craniofacial development
skull
lower jaw
mandible
embryonic cartilage
embryonic bone
On-line přístup:https://www.frontiersin.org/articles/10.3389/fgene.2022.871927/full
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