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No Adaptation of the Prion Strain in a Heterozygous Case of Variant Creutzfeldt-Jakob Disease

We investigated a clinical case of variant Creutzfeldt-Jakob Disease in a person heterozygous for methionine/valine at codon 129 of the prion protein gene and identified the same strain properties in variant Creutzfeldt-Jakob disease in methionine homozygous persons and in bovine spongiform encephal...

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Main Authors: Aileen Boyle, Chris Plinston, Fraser Laing, Graeme Mackenzie, Robert G. Will, Jean C. Manson, Abigail B. Diack
Formato: Artigo
Idioma:Inglês
Publicado em: Centers for Disease Control and Prevention 2020-06-01
Colecção:Emerging Infectious Diseases
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Acesso em linha:https://wwwnc.cdc.gov/eid/article/26/6/19-1116_article
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