Isoform‐specific effects of transcription factor TCFL5 on the pluripotency‐related genes SOX2 and KLF4 in colorectal cancer development

Colorectal cancer (CRC) is a very common life‐threatening malignancy. Transcription factor‐like 5 (TCFL5) has been suggested to be involved in CRC. Here, we describe the expression of four alternative transcripts of TCFL5 and their relevance in CRC. Complete deletion of all isoforms drastically decr...

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Bibliographic Details
Main Authors: Javier Galán‐Martínez, Konstantinos Stamatakis, Inés Sánchez‐Gómez, Silvia Vázquez‐Cuesta, Núria Gironés, Manuel Fresno
Format: Artigo
Language:Inglês
Published: Wiley 2022-05-01
Series:Molecular Oncology
Subjects:
colorectal cancer
isoforms
KLF4
SOX2
TCFL5
Online Access:https://doi.org/10.1002/1878-0261.13085
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